Certified Clinical Research Coordinator (CCRC) Practice Exam

What is considered one of the most challenging aspects of conducting clinical trials?

1. Recruitment of qualified participants

2. Cost management

3. Data analysis

4. Regulatory compliance

The correct answer is: Recruitment of qualified participants

Recruitment of qualified participants is often cited as one of the most challenging aspects of conducting clinical trials due to several factors. First, finding individuals who meet the specific eligibility criteria set forth in the study protocol can be difficult, especially if the criteria are strict. Many studies target specific populations, such as those with particular diseases or health conditions, which can significantly narrow the pool of potential participants. Moreover, potential candidates may have concerns about participating in a clinical trial, including fears about the trial process, possible side effects, or the informed consent process. This can lead to hesitancy or refusal to participate, making effective recruitment strategies essential. Successful recruitment often requires extensive outreach and education about the trial, which can be resource-intensive. In addition, competition among multiple studies for the same population can hinder recruitment efforts. At times, if a trial does not recruit enough participants within the required timeline, it could result in delays, increased costs, or even the cancellation of the study. While cost management, data analysis, and regulatory compliance are also significant challenges faced in clinical trials, the recruitment of qualified participants stands out as particularly complex, as it directly impacts the trial's validity and feasibility. Inadequate recruitment not only delays the progress of research but can also fundamentally affect